@mrpalmtree34 You have to relaunch the game. One similar bug happened when I was fighting an order of ancient that he could almost recover from any damage I did every 3 or 4 seconds if I stopped attacking, so if I could not one hit kill him or attack nonstop, he was invincible(but I believe even I can one hit kill him, I still can't loot because he would still be recovering with the ragdoll lying on the ground, just like the problem OP encountered).

@mrpalmtree34 You have to relaunch the game. One similar bug happened when I was fighting an order of ancient that he could almost recover from any damage I did every 3 or 4 seconds if I stopped attacking, so if I could not one hit kill him or attack nonstop, he was invincible(but I believe even I can one hit kill him, I still can't loot because he would still be recovering with the ragdoll lying on the ground, just like the problem OP encountered).

I don't think it's a hardware problem, at least it needs to be fixed. I have played many hours and only encountered once, my PC froze for seconds and rebooted. I'm using a 3700X and a 5700XT.

1 Sometimes enemies including wild animals can instantly kill me with only one finishing move even my health gauge is full;
2 This one might be widely reported that weapon would drop on the ground when using torch and it can never be picked up again, this needs to be fixed soon, I have already lost two and one of them is fully upgraded that I really want to get it back;
3 When I was raiding a place, I found a resource chest in a corner that I had to push away the blockade to get to, but there were two pots on the left and one sack in front which I couldn't break so that I couldn't move the blockade, was it that I didn't find the right way or a lapse of designer when placing prefabrications?

One suggestion, if some chests in castles or some buildings that players can't get in for now, why not just block them from players like Ghost of Tsushima using heavy fire to notify players to push the story? I heard that many players had wasted so much time on finding the right entrance of a building, which needs to finish the specific story mission to open the gate of it, to have the chest.