@ajcollyer I'm on xbox one and having the same issue; its really weird because I had already gone past this point with no issue, then came across another critical point I couldn't interact with, and restarted the game.

Was on the cruel destiny mission, and when trying to get through the outer gate, I couldn't interact with it. Even tried reloading it from an earlier save and nothing.

Then, deciding to just go from the beginning to see if that may help, I can no longer interact with several chests I could before, nor can I free my crew.